Coreg and Heart Failure: Drug Facts, Dosing, and Side Effects

Coreg Drug Facts

Carvedilol or Coreg is used to treat congestive heart failure (condition in which the heart cannot pump enough blood to all parts of the body) and high blood pressure. It also is used to treat people who have had a heart attack. Carvedilol is often used in combination with other medications. Carvedilol is in a class of medications called beta-blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.

Role of Beta-Blockers in Heart Failure

High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. Studies have shown that coreg has the ability to increase the ejection fraction of the heart.

Coreg has also been effective in remodeling the heart. Also, people were admitted to the hospital less frequently when they took Coreg. Mortality and morbidity were also lower in people who took coreg. Large-scale randomized, placebo-controlled trials involving more than 4000 patients with chronic heart failure have demonstrated that carvedilol improves survival and reduces hospitalizations.

Coreg Side Effects

 

CardiovascularBradycardia, interference with normal heart rate, irregular heart rate, slowed atrio-ventricular conduction, atrio-ventricular block, palpitations, cardiac failure, hypotension, orthostatic hypotension, angina, oedema, fluid overload, hypervolaemia, disturbances of peripheral circulation (cold extremities, peripheral vascular disease, exacerbation of intermittent claudication, gangrene in patients with poor circulation and Raynaud’s phenomenon)
RespiratoryDyspnoea, shortness of breath with or without strenuous physical activity, bronchospasm, wheeze, asthma in predisposed patients, nasal congestion, runny nose, flu like symptoms, bronchitis, pneumonia, upper respiratory tract infection
Gastro-intestinalAbdominal pain, dry mouth, nausea, vomiting, constipation, diarrhoea, dyspepsia, flatulence, upset stomach, hepatitis and deranged liver enzymes
Genito-urinaryImpotence, disturbances of sexual desire and performance, erectile dysfunction renal failure and renal function abnormalities in patients with diffuse vascular disease and/or underlying renal insufficiency, micturition disorders, urinary incontinence in women, urinary tract infection
NeurologicalTiredness, dizziness, depression, depressed mood, headache, pre-syncope, syncope, fainting paraesthesia, tingling or pins and needles, muscle cramps, muscle weakness, sleep disorders, nightmares, asthenia, inability to think clearly, sleepiness or difficulty sleeping, change in personality, hallucinations, hearing impairment
Skin & subcutaneous tissuesSkin reactions e.g. sensitivity to light, allergic exanthema, dermatitis, hypersensitivity reactions, angioedema, increased sweating, urticaria, pruritus, psoriatic and lichen planus like skin lesions, alopecia, worsening of existing psoriasis
Metabolism & nutritionDyslipidaemia, hypercholesterolemia, weight gain, impaired blood glucose control, deranged blood glucose control in existing diabetics
HaematologicalChanges in blood results including anaemia, thrombocytopenia and leucopoenia, effects on blood clotting causing unexplained or easy bruising, worsening or new blood vessel disorders
MusculoskeletalJoint inflammation, pain in extremities, myasthenia gravis
Eye disordersVisual impairment, decreased lacrimation and dry eyes, eye irritation, conjunctivitis

 

 

In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

There are some natural alternatives to beta blockers as well. Check out these alternatives below:

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